منابع مشابه
Targeted Delivery of Nanomedicines
The role of targeting of the diseased region by a drug is emphasized. The rationale for resorting to nanomaterials as drug carriers is explained. A clear understanding of the biological environment, its degradation in diseased condition, and the interaction of the drug with it in normal condition and during illness lie at the core of successful drug delivery. Passive and active drug targeting a...
متن کاملRNAi-based nanomedicines for targeted personalized therapy.
RNA interference (RNAi) has just made it through the pipeline to clinical trials. However, in order for RNAi to serve as an ideal personalized therapeutics and be clinically approved-safe, specific, and potent strategies must be devised for efficient delivery of RNAi payloads to specific cell types, which despite the immense potential, remains a challenge. Through evaluating the recent reported...
متن کاملQuantitative self-assembly prediction yields targeted nanomedicines.
Development of targeted nanoparticle drug carriers often requires complex synthetic schemes involving both supramolecular self-assembly and chemical modification. These processes are generally difficult to predict, execute, and control. We describe herein a targeted drug delivery system that is accurately and quantitatively predicted to self-assemble into nanoparticles based on the molecular st...
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ژورنال
عنوان ژورنال: ISRN Pharmacology
سال: 2012
ISSN: 2090-5173
DOI: 10.5402/2012/571394